An experimental study of the rhizosphere effect on phytoremediation of petroleum polluted soil was carried out with three species of grasses, namely Pannicum, Eleusine indica (L.) Gaerth, and Tall Fescue. After a period of 150 days, this pot experiment showed that the rhizosphere of these three species accelerated the degradation of petroleum hydrocarbons to different extents. The results showed that the number of microorganisms in the rhizosphere increased by three orders of magnitude. The induction of the plant rhizosphere and the coercion influence of petroleum changed the species and activity of microorganisms. The degradation of petroleum hydrocarbons in the rhizosphere was 3-4 times that in unplanted soil. The dehydrogenase activity in the rhizosphere was 1.61-2.20 times that in unplanted soil, but the catalase activity was 0.90-0.93 times that in unplanted soil, and soil moisture content increased by 5% compared with the unplanted soil.
Background: Cytokines has the capacity to serve as biomarkers and therapy targets in a number of cancers. The aim of this study was to estimate the diagnostic potential of serum IL-8 in laryngeal cancer.Methods: Serum levels of IL-8 in 126 laryngeal cancer patients and 112 healthy controls were detected using enzyme-linked immunosorbent assay (ELISA) analysis. The association of IL-8 with clinicopathological characteristics was analyzed via χ2 test. Additionally, the receiver operating characteristic (ROC) curve was plotted to evaluate the diagnostic value of serum IL-8 in laryngeal cancer by calculating the area under ROC curve (AUC).Results: Serum IL-8 was significantly increased in laryngeal cancer patients, and its increased expression was positively associated with T classification (P=0.031), clinical stage (P=0.021) and lymph node metastasis (P=0.023). ROC curve suggested that serum IL-8 had a high value in differentiating laryngeal cancer patients from healthy individuals with a AUC value of 0.859 (95%CI: 0.812-0.906) combing with a sensitivity of 86.5% and a specificity of 72.3%.Conclusion: Serum IL-8 was significantly upregulated in laryngeal cancer which may serve as a biomarker for early diagnosis of laryngeal cancer.
Background: Cortactin gene was up-regulated in various human cancers. However, the role of cortactin in the diagnosis of oral squamous cell carcinoma (OSCC) remained unclear. The aim of this study was to investigate the diagnostic value of cortactin in OSCC patients.Methods: The relative mRNA expression levels of cortactin in OSCC tissues and adjacent normal oral mucosal tissues were detected by quantitative real-time polymerase chain reaction (qRT-PCR). Chi-square test was used to analyze the correlation between cortactin expression and clinical characteristics of patients. The diagnostic value of cortactin in OSCC patients was estimated via receiver operating characteristic (ROC) curve analysis.Results: Compared with the normal controls, cortactin mRNA expression was significantly increased in OSCC tissues (P<0.001). Importantly, notable correlations were found between cortactin expression and tumor size (P=0.040), TNM stage (P=0.018), lymph node metastasis (P=0.013) as well as recurrence (P=0.031). Furthermore, the result of ROC curve analysis showed that the area under the curve (AUC) was 0.867 with a sensitivity of 76.2% and a specificity of 86.9%. It revealed that the diagnostic value of cortactin was high in OSCC patients.Conclusions: Our data reveal that cortactin expression is up-regulated in OSCC and correlated with tumor progression. Cortactin may be a potential bio-marker for early diagnosis of OSCC.
BackgroundLncRNA XIST (X-inactive specific transcript) is involved in various tumors. In this study, we aimed to investigate the diagnostic performance of serum lncRNA XIST in NPC.MethodsSerum samples were collected from 117 NPC patients and 80 gender and age matched healthy individuals. The relative expression of serum lncRNA XIST was detected by qRT-PCR. Chi-square test was applied to evaluate the relationship between lncRNA XIST expression and clinical characteristics. ROC analysis was performed to identify the feasibility of serum XIST as a diagnostic biomarker for NPC.ResultsSerum lncRNA XIST was higher in NPC patients than that in healthy volunteers (P<0.001). Furthermore, its elevated expression showed positive link with clinical stage (P=0.013), TNM stage (P=0.024), and lymph node metastasis (P=0.003). ROC curve demonstrated that lncRNA XIST could discriminate between NPC patients and healthy individuals, with the AUC value of 0.827. The cut-off value of serum XIST for NPC diagnosis was 3.735, with the sensitivity of 75.2% and specificity of 83.7%.ConclusionLncRNA XIST as an oncogene plays promoting roles in aggressive progression of NPC. Serum lncRNA XIST may be employed as a diagnostic biomarker for NPC.
Background The aim of this study was to assess the prognostic value of Krüppel-like factor 7 (KLF7) for patients with oral squamous cell carcinoma(OSCC). Methods The expression of KLF7 was detected by quantitative real-time polymerase chain reaction (qRT-PCR) in pairs of tumor tissues and adjacent non-tumor tissues of OSCC. Chi-square (χ2) test was applied to evaluate the association of KLF7 expression with clinicopathological characteristics of OSCC patients. Overall survival was estimated using the Kaplan-Meier method with log rank test. The cox proportional hazards model was used for univariate and multivariate analyses. Results The expression of KLF7 was remarkably increased in OSCC tissues compared with adjacent non-tumor tissues (P < 0.001). KLF7 expression was related to TNM stage (P = 0.006), tumor size (P = 0.010), smoking (P = 0.006) and drinking (P = 0.000). Kaplan-Meier analysis showed that OSCC patients with high KLF7 expression had a poorer overall survival than those with low expression (log rank test, P = 0.018). Moreover, multivariate analyses showed that KLF7 was an independent prognostic factor for OSCC (P = 0.002 HR = 2.645 95%CI: 1.426–4.906). Conclusion Decreased expression of KLF7 may be a potential unfavorable prognostic factor for patients with OSCC.
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