Background:The Malaysian nurses encounter many barriers in their involvement in clinical research [and also in research utilization (RU)]. Objective: This cross-sectional survey utilized a self-administered questionnaire within a study population of the Malaysian nurses working in a government hospital to determine the level of involvement of nurses in clinical research at Hospital Putrajaya from May to August 2015, which led to an assessment of the level of association between a list of pre-specified demographic and job-related characteristics and the involvement of nurses in clinical research, in order to identify any plausible factors which might have an association with either facilitating or hindering these nurses from their involvement in clinical research. Methods: After having prepared and validated the self-administered questionnaires for this study, they were then distributed to a total of 406 nurses working in Hospital Putrajaya. This self-administered questionnaire was specifically designed to achieve the objectives of this study which aimed to collect the baseline socio-demographic information of the respondents, and also information pertaining to their nursing practice and their participation in activities that were related to nursing research. Results: This study had provided some valuable insights into several plausible factors that were associated with the low level of involvement of Malaysian nurses in clinical research. Conclusion: The study provides valuable information for formulating strategies to increase nurses' participation in research activities at Hospital Putrajaya by providing more research training opportunities and enhancing the level of awareness and increasing the accessibility to these resources by the nurses.
Health-related quality of life (HRQOL) is one of the most important outcome measures to be assessed by medical research. This study aims to develop and validate an instrument called the “health-related quality of life with six domains” (HRQ-6D), which aims to measure an individual’s health-related quality of life within a 24 h period of time. This is a questionnaire development study involving five phases, which are (i) to explore the subject matter content for gaining a better understanding of the topic, (ii) to develop the questionnaire, (iii) to assess both its content validity and face validity, (iv) to conduct a pilot study, and finally, (v) to undertake a field testing of the questionnaire. For the field-testing phase, a cross-sectional study involving a self-administered survey for HRQ-6D items was conducted among healthcare workers with various health conditions. Exploratory factor analysis was initially applied to construct the major dimensions of the HRQ-6D. Confirmatory factor analysis was subsequently applied to evaluate the model fit of the overall framework of the HRQ-6D. The clinical utility of this HRQ-6D was also assessed via its association with actual clinical evidence. A total of 406 respondents participated in the survey. Six domains were identified from the analysis, namely “pain”, “physical strength”, “emotion”, “self-care”, “mobility”, and “perception of future health” comprising two items in each domain. Each domain was reported to have a minimum value of Cronbach’s alpha of 0.731, and the model fit for the overall framework of the HRQ-6D was also found to be excellent. Exploratory factor analysis was undertaken for the 12 items of the HRQ-6D. All the domains can be categorized into three major dimensions, namely “health”, “body function”, and “future perception”, with a minimum value for their factor loadings of at least 0.507. A notable finding was that the HRQ-6D was significantly associated with an individual’s existing comorbidities and current status of health (p < 0.05). This study successfully validated the HRQ-6D, and we found it to possess both excellent levels of reliability and validity and a satisfactory degree of model fit; it was also significantly associated with actual clinical evidence.
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