Epidemic gastroenteritis was transmitted to human volunteers by the oral administration of fecal filtrates. The original inocula were obtained from patients in a natural outbreak which occurred at Marcy State Hospital in the winter of 1946–47. The experimental disease closely resembled that of the donors. The incubation period ranged from I to 5 days, with a mean of 3 days. The disease was carried through three generations, in the last two by means of fecal filtrates.
Oral administration of unfiltered throat washings from experimental cases of the disease likewise induced gastroenteritis but subjects who inhaled a portion of the same throat washings remained asymptomatic. Volunteers who inhaled throat washings taken from patients in the epidemic at Marcy State Hospital also failed to develop the disease.
Five volunteers who had previously been inoculated with fecal filtrates were reinoculated with the same material. Gastroenteritis followed in one of the two subjects who had failed to contract the disease the first time. The others remained well.
Embryonated hens' eggs were inoculated with one of the two unfiltered stool suspensions used in the pool which had induced gastroenteritis in each of the three volunteers to whom it was fed. Three sets of eggs were inoculated: one on the chorioallantoic membrane, another into the yolk sac, and a third into the amniotic sac. Three serial passages were carried out by each method at varying time intervals. Penicillin and streptomycin were employed as antibacterial agents. Tissue and extraembryonic fluids from the third passage were non-infective for volunteers.
T HIS study was designed to test the systematic studies of the effect of efficiency and practicality of ultra-ultra-violet irradiation of military barviolet irradiation as a method of racks has not heretofore been reported. reducing the spread of respiratory Such semi-isolated military cominfection in Navy barracks. In a more munities offer advantages for controlled general sense it was also hoped that a epidemiological studies which are not controlled study of this type on a large to be found in most civilian groups. The scale might give information on the population under observation can be amount of irradiation required for effec-very large, yet at the same time accurate tive control and the differential effect figures are available as to its precise exerted on various diseases of viral and strength from day to day. Also, in such bacterial origin. controlled populations all illnesses from While considerable information is the dispensary visits for minor comnow available as to the effect of ultra-plaints to more serious cases requiring violet light in reducing cross-infections hospitalization are known and classified in hospital wards, curtailing the inci-by the medical officers of the unit, and dence of epidemic respiratory diseases complete data on respiratory morbidity in schoolrooms and sterilizing the air in the study population can be recorded about the patient in operating rooms, and analyzed. Finally, the nature of _________ such semi-enclosed recruit communities
PUBLIC HEALTH WORKERS share a common concern over a critical issue of our time: Federal grants.where are they leading public health? It may be as Jonathan Swift once said, "We are so fond of one another be¬ cause our ailments are the same." This does not imply that we regard Federal assistance as an ailment. On the contrary, we recognize the grant as a prescription for our public health problems.but a prescription with side effects
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