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Metal complexes of some divalent metal ions (Co, Ni, Cu and Zn) with 3-(?- acetylethylidenehydrazino)-5,6-diphenyl-1,2,4-triazine (AHDT) as a Schiff-base have been investigated potentiometrically and spectrophotometrically and found to have the stoichiometric formulae 1:1 and 1:2 (M:L). The formation constants of the proton-ligand and metal-ligand complexes have been determined potentiometrically at different temperatures (10, 20, 30, 40 and 50?C) at an ionic strength of 0.1MKNO3 in 75%(v/v) dioxane-water solution. The standard thermodynamic parameters, viz. ?Go, ?Ho, and ?So, for the proton-ligand and the stepwise metal-ligand complexes have been evaluated.

A series of Schiff bases (L1–L4) that possess in their structure bioactive sulfonamide group and their nickel (II) complexes have been synthesized. Microanalytical analyses, various spectroscopic methods such as Fourier transform infrared spectroscopy (FT‐IR), 1H nuclear magnetic resonance (NMR), 13C NMR, UV–Vis, and MS, are used to explore the nature of bonding and to elucidate the chemical structures. The analytical and magnetic values suggest a range of stoichiometries 1:1, 1:2, and 2:1 (M:L) for the synthesized complexes of almost square planar geometry. The spectral comparative interpretation reveals that L1 and L2 coordinate to the central Ni (II) in tetradentate ONON donor sequence, whereas L3 and L4 in bidentate ON pattern through deprotonated phenolic‐O and the azomethine‐N. Density functional theory (DFT) and MOE‐docking approaches are used to evaluate the molecular parameters and the binding propensity of the synthesized ligands and their complexes with 3s7s protein and to signify their inhibition strength. Besides, the anticancer, antimicrobial and antifungal activities have been screened against number of tumor cells and human pathogen strains. These in vitro studies reveal that Schiff base L4 and its complex, [Ni(L4‐H)(OAc)(H2O)], have superior activities reflecting the importance of inserting bioactive pendant substituents such as thiazole ring and 3‐fluorophenylazo to the pharmacophoric sulfonamide moiety. Moreover, some of the synthesized Ni (II) complexes display promising therapeutic effects as novel non‐platinum antitumor agents after further preclinical investigations.

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Preparation and chemical analysis of Mn(II), Fe(III), Co(II), Ni(II), and Zn(II) complexes with Schiff base L [o-HOC 6 H 4 CH:N(CH 2 ) 6 N:CHC 6 H 4 OH-o] are the main tasks of this work. The octahedral (M 2 L 2 ⋅nH 2 O⋅X) complexes in 1 : 1 M : L ratio (X = NO 3 − or Ac − group, L = ligand) were prepared by involving the hydroxylic group in ortho position. All complexes were characterized on the basis of elemental analysis, UV, IR, 1 H NMR, Gc/Ms, thermogravimetric analysis, magnetic measurements, molar conductance, and electrical conductivity. The obtained data indicate that all the investigated compounds behave as semiconductor materials. Schiff Base L (HBS). The ligand was synthesized by slowly adding salicylaldehyde (5.47 mL, 44.86 mmole) in 100 mL methanol to 1,6-hexanediamine (3 g, 25.81 mmole). The reaction mixture was heated to reflux for 2 hr. The yellow product obtained was filtered off and washed with few amount of methanol and then diethylether, and fine crystals were Submit your manuscripts at Synthesis of N, -Hexamethylenebis(Salicylideneimine)

Single phase LiCo 1−y Ni y O 2 (y=0.4 and 0.5) with fine particles and high homogeneity was synthesized by "chimie douce" assisted by citric acid as the polymeric agent and investigated as positive electrodes in rechargeable lithium batteries. The long-range and short-range structural properties are investigated with experiments including X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and superconducting quantum interference device magnetometry. The physicochemical properties of the powders (crystallinity, lattice constants, grain size) have been investigated in this composition. The powders adopted the α-NaFeO 2 structure as it appeared from XRD and FTIR results. Magnetic measurements shows signal at low temperature attributed to the magnetic domains in the nanostructure sample from which we estimated that the cation mixing are 3.35 and 4.74% for y=0.4 and 0.5 in LiCo 1− y Ni y O 2 , respectively. LiCo 0.5 Ni 0.5 O 2 cathode yields capacity (135 mAh g −1 ) compared to LiCo 0.6 Ni 0.4 O 2 cathode (147 mAh g −1 ) when discharged to a cutoff voltage of 2.9 V vs. Li/Li + . Lower capacity loss and higher discharge efficiency percentage are observed for the cell of LiCo 0.6 Ni 0.4 O 2 cathode.