To evaluate the clinical outcomes of m a c u l a r l a s e r p h o t o c o a g u l a t i o n a f t e r t h e intravitreal injection of 4 mg of triamcinolone acetonide (IVTA) for diffuse diabetic macular edema (DME).Methods: Eighty-six eyes of 74 patients with diffuse DME were randomized into 2 groups. The laser group eyes (n=48) were subjected to a macular grid laser photocoagulation 3 weeks after IVTA. The control group eyes (n=38) underwent only IVTA. Both groups were compared with regard to the changes in visual acuity and central macular thickness at 3 weeks, 3 months, and 6 months after IVTA.Results: Themeancentralmacularthicknessbefore,3weeks after, and 3 and 6 months after IVTA were 538, 250, 295, and 301 µm in the laser group vs 510, 227, 302, and 437 µm in the control group, respectively. The logMAR visual acuities were not significantly different between the 2 groups at baseline and at 3 weeks after IVTA but were significantly better in the laser group at 3 (P=.02) and 6 months (PϽ.001) after IVTA.Conclusions: Macular laser coagulation effectively maintains improved visual acuity after IVTA for diffuse DME and is believed to reduce recurrent DME after IVTA.
Lipogranuloma can develop in the eyelid following autologous fat injection to the forehead or glabella. Clinicians should be aware of this potential complication of a granulomatous reaction following autologous fat injection. Techniques for the injection and preservation of autologous fat should be refined.
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