Nail changes in leprosy are multifactorial, and could be related to one or more of the following: neuropathy, endarteritis, trauma, drugs or superimposed infections. Nail changes in leprosy may be used as an additional clue that helps in the diagnosis.
The global widespread of coronavirus disease 2019 (COVID-19) has caused shortage of medical face masks and led to developing of various types of cloth masks with different levels of protection and comfort to meet the market demands. Breathing comfort is a significant aspect that should be considered during the design of cloth masks along with the filtration efficiency; otherwise, the wearer will feel suffocated. In this work, different types of cotton and polyester knitted fabrics blended with spandex yarns were produced and treated with silver nanoparticles to be used as antiviral cloth masks. Scanning electron microscope, transmission electron microscope, and EDX were used to characterize the silver nanoparticles (AgNPs). Antiviral activity was assessed against SARS-CoV-2 coronavirus as well. The influence of using different fabric materials, number of layers, and hybrid layers on their air permeability and breathability were investigated to evaluate the comfortability of the cloth masks. Physiological impacts of wearing the cloth masks were evaluated by measuring oxygen saturation of hemoglobin and heart rate of the wearers while doing various activities. The results indicated that AgNPs have low cytotoxicity and considerable efficiency in inhibition of SARS-CoV-2. Adding spandex yarns with different count and ratios reduced the porosity and air permeability of the fabrics. Moreover, the combination of three hybrid layers’ mask made of polyester fabric in the outer layer with 100% cotton fabric in the inner layer showed high comfortability associated with high air permeability and breathability. Also, wearing these masks while doing activities showed no significant effect on blood oxygen saturation and heart rate of the wearers.
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