Comparative study has been made histologically and micrometrically on the senile changes of the kidney between Caucasians and Japanese. In both races, weight loss of the kidney, decrease in number of the parenchymal cells and tendency to increase in size of the cells were considered to be main characteristics of the senile changes, but in the process of the senile changes some differences were noticed between the two races. The race differences may be partly due to the difference in the process of sclerotic changes of the intrarenal arteries. These differences have been discussed with special consideration to the nutritional conditions of the two races.
Comparative micromeasuring studies have been made on the senile changes of the skeletal muscle tissues of the rats. The senile decrease in weight of the skeletal muscle was observed to be due to decrease in number and in volume of the muscle fibers; in case of the white fibers, the senile decrease was due mainly to a decrease in volume, on the contrary, in case of the senile change of the red fibers, there was noticed a marked decrease in number of the fibers without distinct decrease in volume. These differences in the decrease in number and volume between the two kinds of muscle fibers were statistically significant. Some discussions have been made on the difference in the process of senile changes between the two types of the muscle fibers with special references to their morphology and function.
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