Effectiveness of permethrin standard and modified methods in scabies treatment Abstrak Latar belakang: Permetrin adalah obat pilihan untuk terapi skabies tetapi memiliki efek samping eritema, nyeri, gatal dan rasa menusuk. Pengobatan standar dengan mengoleskan permetrin ke seluruh tubuh menimbulkan ketidaknyamanan sehingga timbul pemikiran memodifikasi metode pengobatan skabies dengan cara mengoleskan permetrin di lesi saja diikuti mandi dua kali sehari memakai sabun. Tujuan penelitian ini untuk mengetahui efektivitas permetrin metode standar dibandingkan dengan metode modifikasi dalam pengobatan skabies. Metode: Penelitian eksperimental ini dilakukan di sebuah pesantren, Jakarta Timur dan pengambilan data dilakukan pada bulan Mei-Juli 2012. Diagnosis skabies ditetapkan dengan anamnesis dan pemeriksaan kulit. Subyek positif skabies dibagi menjadi tiga kelompok: satu kelompok metode standar (permetrin dioleskan ke seluruh tubuh) dan dua kelompok modifikasi (permetrin hanya dioleskan di lesi diikuti mandi memakai sabun biasa dan sabun antiseptik). Ketiga kelompok dievaluasi setiap minggu selama tiga minggu berturut-turut. Data diolah dengan SPSS versi 20 dan dianalisis dengan uji Kruskal-Wallis.
Introduction: The asbestos industry actively tries to delay adequate asbestos protection regulation in workplaces by systematic manipulation and scientific misconduct. This research aims to compile several of their efforts throughout the years to study their efforts and prevent them. Methods: A literature review was conducted to explore instances of scientific misconduct in occupational health studies related to asbestos in November 2022. The sources were taken from Google Scholar and PubMed. From the entire search, 6 relevant studies were reviewed. Results: Throughout the world, the asbestos industry has been responsible for delays in adequate asbestos regulations. Several systematic scientific misconduct regarding asbestos use happened in 1930s United States, as well as fraudulent research regarding asbestos in early 2000s Brasil. Scientific misconducts can directly influence the direction of occupational health research involving asbestos exposure, resulting in delays in adequate regulation implementation.Conclusions: The dangers of asbestos to workers exposed is already firmly established. The asbestos industry has been deliberately manipulating scientific data to sway corporate and public views to prolong the viability of asbestos production and daily use. They achieved this using industry-backed scientific discourse, direct manipulation of research data, as well as direct manipulation of research data publication.
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