Reactions of alkynes with arenes proceeded in the presence of dinuclear palladium complexes and trialkylboranes to yield alkyne hydroarylation products with high stereoselectivity. In the reactions of monosubstituted benzenes, meta and para products were formed in statistical ratios, while no ortho isomers were detected.
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Stereoselective cis-Addition of Aromatic C-H Bonds to Alkynes Catalyzed by Dinuclear Palladium Complexes. -Dinuclear palladium complexes like FAM catalyze the cis-hydroarylation of internal alkynes with arenes to give the products exclusively with (E)-configuration. Regioisomeric mixtures of (E)-products in statistical ratios are obtained if alkyne (Ia) reacts with monosubstituted arenes. In addition, chemical experiments are made to elucidate the role of boranes in the hydroarylation . -(TSUKADA*, N.; MITSUBOSHI, T.; SETOGUCHI, H.; INOUE*, Y.; J. Am. Chem.
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