Three female patients, two under 35 years old, presented with ruptured aneurysms of the distal anterior inferior cerebellar artery (AICA) manifesting as subarachnoid hemorrhage. The first patient had a ruptured saccular aneurysm of the meatal loop of AICA, which was treated by direct neck clipping. The second patient had a ruptured aneurysmal lesion that arose from a microvascular anomaly of the dorsolateral portion of the AICA, which was successfully treated by trapping. The third patient was dead on arrival, and autopsy revealed a ruptured saccular aneurysm in the meatal loop of the AICA. The mechanism of development of distal AICA aneurysm remains unclear, and some cases indicate a complicated causal relationship between the aneurysms and vascular anomalies. Neurosurgeons need to carefully evaluate the vascular structure around the aneurysms by preoperative angiography in each case, and select the most appropriate strategy.
A bacterial strain was isolated from soil, which rapidly degraded purified barley ƒÀ-glucan as well as lichenan. The strain belonged to Bacillus pumilus , and some authentic strains of this species were also shown to hydrolyze the glucan. An enzyme active on the above sub strates but not on laminaran and on CM-cellulose was partially purified from the culture fluid. This enzyme, about 27,000 in molecular weight, was found to cleave a ƒÀ-(1•¨4) linkage adjacent to a ƒÀ-(1•¨3) in the polymers. It was suggested that only an enzyme of this type should be called a 'lichenanase' and discriminated from cellulases and laminaranases.
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