In this paper, the effects of vibrations at high frequencies onto a freely falling two-body system in Schwarzschild spacetime are investigated. As reference motion of the same system without vibrations, a circular orbit around the central body is considered. The vibrations induce a perturbation on this motion, whose period is close to the orbital period, in agreement with the simpler situation of the Shirokov effect [1]. In general relativity, the amplitude of the perturbation is dominated by high-velocity effects, which grow linearly in the radius r of the circular orbit, while the leading term surviving the Newtonian limit decays as 1/r. Thus, even for very large radii a significant difference between Newtonian physics and general relativity is found. We give an estimate of this effect for some molecular vibrations of a system orbiting around the Earth.