To estimate the concentrations of melanin and blood and the oxygen saturation in human skin tissue, we propose a method using a multiple regression analysis aided by a Monte Carlo simulation for diffuse reflectance spectra from the skin tissue. By using the absorbance spectrum as a response variable and the extinction coefficients of melanin, oxygenated hemoglobin, and deoxygenated hemoglobin as predictor variables, the multiple regression analysis gives regression coefficients. The concentrations of melanin and blood are determined from the regression coefficients using conversion vectors that are estimated numerically in advance, while the oxygen saturation is obtained directly from the regression coefficients. Numerical and experimental investigations were performed for layered skin tissue models and phantoms. Measurements of human skin were also carried out to monitor variations in the melanin and blood contents and oxygenation during cuff occlusion. The results confirmed the usefulness of the proposed method.

An experimental investigation to improve the stage efficiency through the use of vaned diffusers is presented. Sixteen different vaned diffusers were tested on a model compressor rig. The results showed that the pressure recovery of the vaned diffuser increased up to the critical diffusion ratio, which was shown to be approximately 0.5. The measured pressure distribution around vanes of the well-designed diffusers which had the fair diffusion ratios, were found to agree well with the potential flow solutions. Finally, the importance of the diffuser inlet configuration to the improvement of the stage efficiency is discussed.

An experimental investigation concerning the optimum relative velocity distribution within impellers, the optimum diffusion ratio of vaned diffusers and the optimum circumferential area distribution, sectional shape of scrolls was carried out using high specific speed shrouded impellers with backward leaning blades. A performance design procedure based on loss analysis and quasi-three-dimensional flow analysis was also developed and modified by introducing experimental results. The design procedure was applied to a 7900-kw four-stage air compressor to demonstrate the usefulness. Field test results of the complete machine showed that the maximum isothermal efficiency was 75 percent with the pressure ratio of 5.96 and the flow rate of 29.3 m3/s.

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A simple method is proposed for visualizing the depth distribution of a local blood region in skin tissue by using diffuse reflectance images at two isosbestic wavelengths of hemoglobin, 420 and 585 nm. Monte Carlo simulation of light transport specifies a relation between optical densities and the depth of the region under given concentrations of melanin in the epidermis and blood in the dermis. Phantom and in vivo experiments were performed to show the usefulness of the method.