Purpose:To analyze the impact of treatment delay caused by COVID-19 infection on patients scheduled for radiotherapy treatment. Methods and Materials: In this descriptive study, we analyzed all patients who were COVID-19 positive during the scheduled radiotherapy course, those who had an infection while on neoadjuvant treatment period, or during surgery before the start of radiation. The study period was from June 2020 to May 2021. A treatment delay was defined as a delay in starting the radiation treatment, a gap during their scheduled radiation treatment, or treatment discontinuation. All patients who had a treatment delay were followed-up till November 2021. Results: The median follow-up time of the study was 13 months. Ninety-four patients were selected for the study who met the inclusion criteria. Seventy-seven patients had a mild COVID-19 infection, while 17 had a moderate to severe illness. Of the entire cohort, 83 patients had a treatment delay. The median treatment delay (MTD) in days was 18 (6 to 47). Amongst those who had a treatment delay, 66 patients were treated with curative intent, of which 51 patients are on follow-up -34 patients are disease-free (MTD -18.5, 10 to 43), seven had either a residual disease or locoregional recurrence (MTD -22, 10 to 32), seven had distant metastasis (MTD -18, 15 to 47), and three patients died (MTD -20, 8 to 27). Of three patients who died, only one died of COVID-19-related causes. Conclusions: Even though the mortality due to COVID-19 infection among those who underwent radiotherapy was low, a treatment delay might have caused adverse treatment outcomes. Longer follow-up of these patients is required to further establish this. It will remain debatable whether it was worth delaying radiotherapy for mild to moderate COVID-19 infection for a significant time to cause a potential cancer treatment failure.
Let F be a finite field and G = GL(6, F ). In this paper, we explicitly describe a certain twisted Jacquet module of an irreducible cuspidal representation of G.
Examples of innovative models have been implemented to tackle the growing problem of limited access to rehabilitation services due to economic, social or political barriers. For example, Interdisciplinary Service Learning (ISL) has been used to introduce students in health professions to a diverse learning environment while allowing clients to
Ancient Egypt furnishes us with examples of different types of sundial from the New Kingdom ( c. 1500 b.c.) onward. Some objects that have been described as sundials are better evidenced as time-keeping devices than others. Hypotheses about the development and even the method of using sundials remain controversial in a few cases. New finds also add to our understanding of the development of sundials in Egypt. Here, we describe an attempt to catalogue ancient Egyptian sundials and the results that are emerging from the investigation.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.