Conclusion Results of this study showed, that hypertensive adolescents have poorer oral health than adolescents with normal BP level. This substantiates the necessity of multidisciplinary approach to management of this group of patients with participation of both pediatric physicians and dentists.
Nasopharyngeal malignant tumors are mainly represented in pediatrics by undifferentiated carcinoma nasopharyngeal tumors (UCNT). It is a rare entity. The aim of our work is to analyze the epidemiological, clinical, therapeutic and evolutionary aspect of children and young £ 20 years with nasopharyngeal cancer. Patients and methods This is a retrospective study of 38 patients diagnosed with a UCNT between January 2012 and December 2018 and treated in the department of oncologyradiotherapy of the CHU Hassan II of Fez. Results The age of our patients was between 10 and 19 years, with a middle age 14.7 years, the most affected age group was 10 to 15 years (70%), the sex ratio was 1.2. Diagnosis is often delayed with a revealing symptoms dominated by cervical adenopathy (85%). 85% of patients were classified T3-T4 and 60% were classified N2-N3 with 4 metastatic patients. Treatment was based on neoadjuvant chemotherapy (in 95% of patients) as well as on concomitant radio-chemotherapy. 3 patients were lost to follow-up. Acute toxicity was characterized by radio mucititis (100%) and radio dermatitis (60%) in patients receiving IMRT radiotherapy, hyposialia (55%), hypoacusis (44%) and trismus%) for those who received 3D conformal radiotherapy, with a lower delayed toxicity for IMRT (only 3 patients who presented with hyposialia). The evolution was marked by a good loco regional control in 55%, a loco regional recurrence in 10%, and remote metastasis in 15%. Thus, the overall survival was 85% and the survival without relapse was 50%. Discussion The prognosis of this cancer remains poor considering the locally advanced forms (high frequency of stages III and IV) and the frequency of recurrences. Conclusion Improving the prognosis of this cancer requires early diagnosis and more accessible and developed medical infrastructures. The recent advances in conformational radiotherapy by intensity modulation will have to be the main technique of treatment of all our patients.
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