Subgroup analyses showed patients undergoing TACE had increased median OS comparing to those who received BSC in both compensated cirrhosis (26.0 VS 9.0 months, Log-rank P<0.001) and early decompensated cirrhosis (14.5 VS 6.9 months, Log-rank P<0.001). In the Cox proportional-hazards model, undergoing TACE is an independent factor associated with prolonged OS in overall patients (Hazard ratio; HR 0.29, 95% CI 0.17-0.49, P< 0.001), compensated cirrhosis (HR 0.31, 95% CI 0.16-0.62, P< 0.001), and early decompensated cirrhosis (HR 0.16, 95% CI 0.061-0.44, P< 0.001).(IDDF2021-ABS-0067 Figure 1, IDDF2021-ABS-0067 Figure 2, IDDF2021-ABS-0067 Figure 3) Conclusions This study demonstrated the beneficial effect of TACE on OS in patients with intermediate-stage HCC who had compensated and early decompensated cirrhosis.
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