Using a miniature strain gauge force transducer implanted in the serosal site of rat proximal colon, we showed that bolus intraperitoneal injection of cholecystokinin octapeptide (CCK-OP) caused partial inhibition of phasic contractile activity of circular muscle which appeared in the fasting state in conscious rats.' This study attempts to ascertain the inhibitory action of CCK-OP and to assess the inhibitory mechanism of this peptide.
We describe a new procedure, which can help patients with obstructive jaundice improve their quality of life (QOL). Although percutaneous transhepatic biliary drainage (PTBD) can relieve jaundice, the procedure has some disadvantages. Percutaneous endoscopic gastrostomy (PEG) is a useful method for providing nutritional support to patients unable to swallow. We have combined these two techniques. We used the combination ofa 20-F catheter and a 9-F jejunal catheter for PEG. The PTBD catheter and the 9-F jejunal catheter are connected outside the patient's body. Externally drained bile from the PTBD catheter can flow back into the jejunum, and the opening between the 20-F catheter and the 9-F jejunal catheter is used for tube feeding. This procedure was adopted in a patient. Since the procedure, the patient's nutritional status and daily living activities have improved. We conclude that the procedure is useful for tube-fed patients with obstructive jaundice.
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