The actually direct Suzuki−Miyaura coupling with "protected" R−B(dan) (dan = naphthalene-1,8-diaminato) was demonstrated to smoothly occur without in situ deprotection of the B(dan) moiety. The use of t-BuOK (Ba(OH) 2 in some cases) as a base under anhydrous conditions is the key to the successful cross-coupling, where R−B(dan) is readily converted into a transmetalation-active borate-form, regardless of the well-accepted diminished boron-Lewis acidity.
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