Although most third-order nonlinear optical (NLO) materials are closed-shell singlet systems, this Letter theoretically shows that the third-order NLO properties are drastically enhanced in symmetric open-shell diradical systems with intermediate diradical character and further reveals that this enhancement is associated with the ferromagnetic and antiferromagnetic interactions. This new paradigm opens up a promising area for designing new third-order NLO materials.
Ones and twos: The two‐photon absorption cross sections (σ(2)) of singlet diradical hydrocarbons with phenalenyl peripheral groups (see scheme) are larger than those of closed‐shell aromatic hydrocarbons by an order of magnitude or more and are comparable to those of π‐conjugated compounds with strong electron donor or acceptor substituents. A significant increase in cross section was also observed in the resonance‐enhanced region.
Understanding the electronic structure of the singlet diradical state tackles the fundamentals of the chemical bond itself. The singlet diradical character is a key factor, which determines the chemical reactivity, the reaction products, as well as the chemical/physical (electronic, optical and magnetic) properties, although this quantity is defined in a purely theoretical manner. In this Letter, on the basis of the valence configuration interaction scheme, we present an explicit connection between the singlet diradical character and measured quantities obtained from one- and two-photon absorption spectra as well as from phosphorescence and electron spin resonance peaks. This enables us to estimate the singlet diradical character experimentally.
BackgroundRobots offer an alternative, potentially advantageous method of providing repetitive, high-dosage, and high-intensity training to address the gait impairments caused by stroke. In this study, we compared the effects of the Stride Management Assist (SMA®) System, a new wearable robotic device developed by Honda R&D Corporation, Japan, with functional task specific training (FTST) on spatiotemporal gait parameters in stroke survivors.MethodsA single blinded randomized control trial was performed to assess the effect of FTST and task-specific walking training with the SMA® device on spatiotemporal gait parameters. Participants (n = 50) were randomly assigned to FTST or SMA. Subjects in both groups received training 3 times per week for 6–8 weeks for a maximum of 18 training sessions. The GAITRite® system was used to collect data on subjects’ spatiotemporal gait characteristics before training (baseline), at mid-training, post-training, and at a 3-month follow-up.ResultsAfter training, significant improvements in gait parameters were observed in both training groups compared to baseline, including an increase in velocity and cadence, a decrease in swing time on the impaired side, a decrease in double support time, an increase in stride length on impaired and non-impaired sides, and an increase in step length on impaired and non-impaired sides. No significant differences were observed between training groups; except for SMA group, step length on the impaired side increased significantly during self-selected walking speed trials and spatial asymmetry decreased significantly during fast-velocity walking trials.ConclusionsSMA and FTST interventions provided similar, significant improvements in spatiotemporal gait parameters; however, the SMA group showed additional improvements across more parameters at various time points. These results indicate that the SMA® device could be a useful therapeutic tool to improve spatiotemporal parameters and contribute to improved functional mobility in stroke survivors. Further research is needed to determine the feasibility of using this device in a home setting vs a clinic setting, and whether such home use provides continued benefits.Trial registrationThis study is registered under the title “Development of walk assist device to improve community ambulation” and can be located in clinicaltrials.gov with the study identifier: NCT01994395.
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