BackgroundTakotsubo cardiomyopathy is rare in pregnancy and is characterized by left ventricular dysfunction with apical ballooning. This transient cardiac dysfunction may affect women of childbearing age in the antepartum, intrapartum or postpartum period. Most patients respond well to medical management with resolution of cardiac dysfunction within weeks.Case presentationA 35-year-old female in her second pregnancy presented with severe preeclampsia at 31 weeks of gestation. She subsequently developed severe substernal chest pain and workup showed a stress induced cardiomyopathy prior to her delivery via caesarean section. She had full recovery of her cardiac function by 12 weeks postpartum after medical management.ConclusionsStress induced cardiomyopathy, though rare, should be considered after acute myocardial infarction has been ruled out in gravid females presenting with acute chest pain. Management should involve a multidisciplinary team. Cardiac function recovery is common within 4 weeks although some patients may require long term heart failure management.
Reserving forced-air warming devices for the treatment of moderate-to-severe hypothermia (<32°C) significantly reduced ICU admissions for AH.
Patient was readmitted to the hospital and treated with cefepime and metronidazole. Positive physical findings were the presence of a high pitched decrescendo diastolic murmur and widened pulse pressure. Transesophageal echocardiogram showed mobile echogenic lobulated mass of the non-coronary cusp of aortic valve with resultant severe aortic insufficiency. The patient received an aortic valve replacement. He was discharged with 6 weeks of intravenous ceftriaxone. CK endocarditis is rare in immunocompetent adults. Our literature search yielded only four prior case reports. Based on our patient's urinary symptoms at presentation along with evidence of pyuria and bacteriuria, this patient's principle infection was likely genitourinary in nature. In conclusion, it is important for clinician's to closely monitor patients with CK bacteremia. If patients have underlying valvular disease, the development of vegetation can be rapid and can be fatal if left undetected.
<div> <p><strong>Introduction: </strong>After orbiting and landing on an ocean world such as Europa or Enceladus, the next step will be to &#8220;rove&#8221;. However, rather than traveling along the surface, a cryobot probe would instead vertically traverse in order to reach the ocean and explore for signs of life. Many challenges exist for technologies to function within the harsh conditions at ocean worlds, including extreme temperatures, pressures, faulting, and the presence of potentially corrosive chemicals. Yet, these must be overcome. In order to return valuable science and engineering data, cryobot communication devices must be capable of transmitting data after deployment through ice shells of a few to 10s of km thick, and over mission lifetimes of several years.</p> <p>A strategy for cryobot communication that employs both optical tethers coupled with radio frequency (RF) relays has been suggested as part an ocean world cryobot mission architecture (e.g. Oleson et al., 2019). Here we present work on a NASA Concepts for Ocean worlds Life Detection Technology (COLDTech) project called Signals Through the Ice (STI) Tech for Ocean Worlds (OW), that builds on previous NASA SESAME STI work, to develop communication hardware solutions (e.g. Craft et al., 2022).</p> <p><strong>Technology developments:</strong> Building on previous characterizations of optical tether robustness shear testing (Singh et al, 2022<em>& in review; </em>McCarthy et al., <em>this meeting</em>), RF relay antenna design (Lorenz et al, 2022), and modeling efforts to characterize Europa&#8217;s ice shell conditions (Walker et al., 2020), the OW STI Tech team is expanding efforts to consider conditions at Enceladus and other factors affecting cryobot communication technologies.</p> <p><em>Optical Tethers</em>. A main hazard for tethered communication is the potential faulting activity inducing strain on the tether and causing data transmission reduction, or even severance the tether. Numerical models have been performed to simulate fault slip resulting from tidal forcing at multiple time points during one Europa tidal cycle. Calculations at multiple time points allow consideration of motion throughout the orbital cycle and evaluates the accumulation of strain on a tether crossing a fault at a range of different strikes, angles, and depths (Lien et al., 2022 & <em>in prep</em>). Calculations have also been performed to constrain Europa's deformation induced by tidal forcing and how it affects the thermal equilibrium state of the ice shell (Walker and Rhoden, 2022). Improving our understanding of the temperature&#160;and heat profiles within ice shells provides important estimates of the specific temperature and pressure environments both tethered and RF technologies will encounter on their journey through an ice shell.</p> <p>Also, a factor not yet constrained for ocean worlds is how a tether&#8217;s jacket material would potentially adhere to the ice. This ice-tether behavior would influence the resulting strain induced on the optical fibers during fault motion. Adhesion tests and design trades on candidate jacket and strength layer materials are in progress with a focus on making improvements for Europa and Enceladus temperatures, strain, and chemical conditions. Additionally, tethers are undergoing environmental chamber &#8220;soaks&#8221;, with tethers embedded in ice of different compositions for months. Material degradation and transmission performance is measured during and upon removal.</p> <p><em>RF relays.</em> An initial RF relay thermo-mechanical design is undergoing evaluation to assess if the essential elements that must be housed and thermally insulated in an Europa or Enceladus ice shell can be kept at the necessary operational conditions. Essential components include batteries, power/heating elements, electronics, and antennas. Prototypes are being built and will undergo thermal and mechanical environmental tests (including thermal balance and rapid & cyclic loading).</p> <p><strong>Summary: </strong>Development of optical tethers and RF relay devices for communication through ice on ocean worlds is underway by the OW STI Tech team. Through modeling of the extreme conditions at Europa and Enceladus, design and build of prototypes, and thermo-mechanical testing, these technologies will be robust to the environmental conditions and will therefore enable the search for extraterrestrial life in the subsurface of ocean worlds.</p> <p><strong>Acknowledgments:</strong> We would like to acknowledge funding from grants 80NSSC19K0613 and 80NSSC21K0995 for this work.</p> <p><strong>References: </strong></p> <div> <p>Craft et al. (2022) <em>53<sup>rd</sup> LPSC</em>, Abstract #2753<em>. </em></p> <p>Lien et al. (2022) <em>AbSciCon</em>, Abstract #518-05.</p> <p>Lorenz et al. (2022) <em>NETS, </em>May, 2022, Cleveland.</p> <p>Oleson et al. (2019) Europa Tunnelbot, <em>NASA/TP</em>&#8212;2019-220054.</p> <p>Singh et al. (2022) <em>AbSciCon</em>, Abstract #518-02.</p> <p>Walker and Rhoden (2022),<em> PSJ,&#160;</em>accepted<em>.</em></p> <p>Walker et al. (2020) <em>51<sup>st</sup> LPSC</em>, Abstract #2448.</p> </div> </div>
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