Fused pyridine derivatives R 0450 Facile Regioselective Synthesis of Pyrazolo[5,1-a]isoquinolines via Ring-Opening Cyclization/Oxidation Reactions of Stable Aroyldiaziridines of 3,4-Tetrahydroisoquinoline with Alkynes. -Novel stable aroyldiaziridines (III) are prepared and their cycloaddition reaction with acetylenes is investigated. The product selectivity is found to depend on the reaction atmosphere since oxygen promotes the conversion of primary products (V) to pyrazoloisoquinolines [cf. (XII)]. -(ORTEGA, H.; AHMED, S.; ALPER*, H.; Synthesis 2007, 23, 3683-3691; Dep. Chem., Univ. Ottawa, Ottawa, Ont. K1N 6N5, Can.; Eng.) -Mais 16-165
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