Prednisolone is a corticosteroid, it works on immune system to relieve swelling, redness, and inflammation.it is a choice of drug for arthritis, cancer, asthma, allergic condition, bell's palsy, Nephrotic syndrome and disorders of endocrine system. Prednisolone helps decreasing inflammation by suppression of leukocytes and decrease expression of pro-inflammatory markers. Nephrotic syndrome is a condition in which damage kidney glomeruli which leaks protein into urine from blood. In pediatric population the choice of drug selected is prednisolone which resolves the symptoms and reduces infection. Prednisolone is the drug considered for the frequently relapsing Nephrotic syndrome. It should be given on alternate basis. for patient with infrequent relapses, therapy should be not prolonged. Adverse effects of prednisolone are hypertension, adrenal suppression, osteoporosis, diabetes mellitus, poor growth and cushingoid syndrome. Systemic toxicity due to prednisolone in pediatric patient increases the risk of infection and pre-renal failure. In this case report, it is summarized that despite of everyday prednisolone intake, alternate day therapy is more effective and causes less side effects. Proper monitoring is necessary and timely laboratory findings should be obtained for less adverse events.
Tetralogy of Fallot is a type of critical congenital heart disease that reduces the amount of oxygen delivered to the body in which adults usually live past the age of 21. Despite the fact that the average life span of a patient with Tetralogy of Fallot who does not have surgery is 12 years, it is believed that approximately 10% of patients live to be 21 years old. Tetralogy of Fallot affects around 3.5% of newborns with congenital cardiac disease, or one in 3600 or 0.28 out of every 1000 live births. Males and females are similarly affected. The majority of patients begin to show symptoms in childhood such as fatigue, shortness of breath and cyanosis needing early intervention. We described a case of a man in his early 20s who postponed the operational procedure despite being identified with Tetralogy of Fallot at the earliest possible stage. A few instances of asymptomatic middle-aged individuals surviving have been documented, and the number is declining as a result of early detection. The example demonstrates the viability of detecting such events in an adult patient despite breakthroughs and growth in medicine.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.