Coronaviruses commonly infect the respiratory tract, leading to severe pneumonia. Respiratory problems cause numerous acid-base disorders in 2019 Coronavirus Disease (COVID-19) patients. Several studies have explored laboratory biomarkers used in the management and prognosis of COVID-19 patients during this pandemic; however, only a few focused on blood gas analysis. Determine the blood gas analysis pattern and its association with the outcome of severe COVID-19 patients treated in the Intensive Care Unit (ICU). This retrospective cohort study used secondary data from patients with severe COVID-19 treated in the ICU of Hasanuddin University Hospital between January and December 2021. There was a higher number of male (58.8%) compared to female patients (41.5%), with a mean age of 62 years. Respiratory alkalosis was the most prevalent blood gas disorder (24.4%). Metabolic alkalosis was a blood gas disorder with the highest number of recovery/improvement outcomes (8 patients). There was no significant relationship between blood gas analysis results and the outcome of severe COVID-19. In addition, no specific pattern was found in the results of blood gas analysis. Respiratory alkalosis was the most frequent blood gas disorder detected in these patients.
Background: Transfusion is an additional therapy in the case of hematology and non-hematology. However, it can be detrimental due to its side effects ranging from mild to severe reactions. This study aimed to determine the relationship of blood types, blood components, and the age of patients with the degree of transfusion reaction. Methods: A retrospective study with secondary data of the patients experiencing transfusion reactions was conducted from January 2017 to December 2019. The population included all patients receiving a transfusion of blood products. The sample met the inclusion criteria, such as the medical records of patients who experienced transfusion reactions during and after the transfusion. The exclusion criteria were cryoprecipitate blood components. Data were analyzed using SPSS version 20 for Windows. Results: Among 228 subjects, there were a higher number (52.60%) of females than males (47.40%). The majority of patients ranged within 40-59 years old (52.70%). Most blood types were O (53.00%), while the dominant blood component was PRC (packed red cell) (50.30%). There was no significant relationship between blood types, blood components, and the age of patients with the degree of transfusion reaction (p>0.05).Conclusion: There was no significant relationship between blood types, blood components, and the age of patients with the degree of transfusion reaction.
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