Ernst et al. HSP90i Augments Radiotherapy-Induced Immune Priming priming of allogeneic T cell responses in vitro. In summary, HSP90 inhibition-apart from its radiosensitizing potential-obviously enables and supports the initial steps of anti-tumor immune priming upon radiotherapy and thus represents a promising partner for combined modality approaches. The therapeutic performance of such strategies requires further in-depth analyses, especially for but not only limited to CRC.
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