Marital status has long been recognized as an important prognostic factor for many cancers, however its’ prognostic effect for patients with laryngeal cancer has not been fully examined. We retrospectively analyzed 8834 laryngeal cancer patients in the Surveillance Epidemiology and End Results database from 2004 to 2010. Patients were divided into four groups: married, widowed, single, and divorced/separated. The difference in overall survival (OS) and cancer-specific survival (CSS) of the various marital subgroups were calculated using the Kaplan–Meier curve. Multivariate Cox regression analysis screened for independent prognostic factors. Propensity score matching (PSM) was also conducted to minimize selection bias. We included 8834 eligible patients (4817 married, 894 widowed, 1732 single and 1391 divorced/separated) with laryngeal cancer. The 5-year OS and CSS of married, widowed, single, and separated/divorced patients were examined. Univariate and multivariate analyses found marital status to be an independent predictor of survival. Subgroup survival analysis showed that the OS and CSS rates in widowed patients were always the lowest in the various American Joint Committee on Cancer stages, irrespective of sex. Widowed patients demonstrated worse OS and CSS in the 1:1 matched group analysis. Among patients with laryngeal cancer, widowed patients represented the highest-risk group, with the lowest OS and CSS.
The local structures of molten ZnCl2, RbCl and Rb2ZnCl4 are measured with the EXAFS technique. Several models are used to analyse the data, and some structural parameters as well as the radial distribution functions of the nearest-neighbour atoms around Zn or Rb atoms are obtained. The tetrahedra consisting of four Cl atoms around Zn are found to be dominant and stable in molten ZnCl2. The skewed behaviour of the radial distribution function for Rb-Cl in molten RbCl is also found, while the local structures around Rb can be regarded as a persistence of the solid state but with strong short-range disorder. In molten Rb2ZnCl4, a network linked by Zn Cl4 groups is not found and the nearest-neighbour structures around Rb atoms are more disordered than in molten RbCl. This has also confirmed that the EXAFS method can provide reliable information about the nearest-neighbour atom-atom coordination for some molten salts, which is helpful in specifying the painwise interaction potential.
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