The purpose of this study was to examine knowledge about the human papillomavirus and attitudes toward human papillomavirus and human papillomavirus vaccination among Korean female undergraduate students. Moreover, this study sought to identify factors associated with intention to obtain the human papillomavirus vaccine. A cross-sectional study was conducted with 297 Korean female undergraduate students. Data were collected using a self-administered questionnaire. Collected data were analyzed with descriptive statistics, t-test or ANOVA, and stepwise multiple regression analysis. Only 37.8% of the participants were aware of human papillomavirus. The percentage of correct answers for knowledge about human papillomavirus was 40.6%. Factors associated with intention to obtain the human papillomavirus vaccine were: wanting more education about the vaccine, disease severity, knowledge of human papillomavirus, awareness of the human papillomavirus vaccine, human papillomavirus attributes, and susceptibility; these variables accounted 31.6% of the variance in scores for intention to obtain human papillomavirus vaccination. Findings from this study suggested a need for more active education to reduce the risk of human papillomavirus infection among female undergraduate students. Educational programs should be developed and evaluated, specifically focused on disease severity, susceptibility, awareness of human papillomavirus vaccine, and attributes of human papillomavirus.
The two thrombectomy devices were associated with similar recanalization rates and clinical outcomes in patients with AIS caused by BAO. However, Penumbra suction thrombectomy seemed to allow more rapid and complete recanalization than Solitaire thrombectomy.
eCAS in patients with AIS due to proximal ICA stenosis or occlusion appears to be a technically feasible and effective method for achieving good clinical outcomes.
Aims: We conducted this study to investigate the independent association of medial temporal atrophy (MTA) and white matter hyperintensities (WMH) with cognitive impairments of Alzheimer’s disease (AD) patients and the interaction between MTA and WMH. Methods: From 13 centers, a total of 216 AD patients were consecutively recruited and their MTA and WMH were visually rated. We evaluated the association of MTA and WMH with the various cognitive domains, and the interaction between MTA and WMH. Results: MTA independently correlated with scores of the Mini-Mental State Examination (MMSE), Clinical Dementia Rating scale (CDR), delayed recalls of the Seoul Verbal Learning Test (SVLT), the Boston Naming Test (BNT), and Word Fluency. WMH independently correlated with MMSE, CDR, Digit Span, and Stroop word reading, but not with delayed recall. There were interactions of WMH and MTA on CDR (p = 0.004), SVLT (p = 0.023), BNT (p = 0.002) and the semantic Word Fluency (p = 0.007). Conclusion: MTA and WMH independently affected cognitive deficits in AD patients, with somewhat different patterns where MTA was associated mostly with memory and language, while WMH were associated with attention and frontal executive functions. This study also showed interactions between MTA and WMH on some cognitive deficits and dementia severity, suggesting that they synergistically contribute to cognitive impairment in AD.
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