Adipose derived stem cells (ASC) can be extracted easily in large quantities with low mortality. ASC have a potential of differentiation toward mesodermal stem cell lineages such as adipogenic, chondrogenic, osteogenic and myogenic pathways and ectodermal stem cell lineage such as neuronal pathway. ASC differentiation may be achieved with specific induction cocktails in culture medium. ASC and differentiated cells could have a pivotal role in fat grafting reconstruction, bone defect healing, muscle reconstruction procedure, and recovery from central-peripheral nerve injury.
Adipose derived stem cells (ASCs) are derived from mesenchyme and have several general or unique characteristics. ASCs have more colony frequency, higher proliferation capacity and can be cultured longer compared with bone marrow-derived mesenchymal stem cells. The yield, frequency of ASCs, the number of viable cells, proliferation and differentiation potential, and growth characteristics of ASCs have various spectrum according to the methods of harvesting, adipose tissue site for harvesting, and patient's individual characteristics.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.