Isolated posterior acute myocardial infarction (AMI) is rare and possibly underdiagnosed. The incidence of misdiagnosis in the emergency department (ED) is unknown. Delayed diagnosis may prevent timely treatment, particularly emergent fibrinolytic therapy. We describe the experience of an urban ED on this rare condition. Methodology: A six years and seven months case series of isolated posterior AMI of initial presentation (as identified by inpatient discharge/death ICD-9-CM diagnosis code) was studied. Patients not admitted from the ED, those who developed isolated posterior AMI only after admission and/or those with concomitant ST segment elevation AMI involving other anatomical locations of the heart (e.g. inferior or lateral walls), were excluded. Results: Eleven cases were included in the study. All the nine cases with electrocardiograms available for review demonstrated features consistent with isolated posterior AMI. Eight out of the eleven (72.7%) cases were correctly diagnosed as isolated posterior AMI in the ED. The other three cases were treated as non-ST elevation myocardial infarction (NSTEMI). Nevertheless, their lack of the typical symptoms of acute coronary syndrome and delayed presentation (more than 12 hours) precluded them from fibrinolytics. Three of the eleven cases received fibrinolytics (all streptokinase). All three cases survived to discharge and there were no haemorrhagic complications. None of the cases underwent emergent percutaneous coronary intervention. Conclusion: The majority of cases with isolated posterior AMI (72.7%) were diagnosed in the ED. Although three cases were interpreted as NSTEMI, the use of fibrinolytic reperfusion therapy was not affected.
To study the utilisation pattern of head computed tomography (CT) for non-trauma adult cases in an urban emergency department (ED) and the rate of clinically significant CT abnormalities. We also tried to identify any useful clinical indicators that could be used to predict abnormal scans. Methodology: A one-year case series of adult non-trauma cranial CT scans ordered in an urban ED was studied. Patients less than 16 years old, with CT head done prior to presentation and/or attendance precipitated by trauma were excluded. Logistic regression was used to identify significant predictors for abnormal scans. Clinical indicators that were studied included age, altered mental status (AMS), headache and vomiting, elevated blood pressure, previous history of hypertension, Glasgow Coma Scale (GCS) and presence of focal neurological sign (FNS). Results: 183 adult non-trauma cranial CT scans were included in the study, and 109 (59.6%) CT scans revealed clinically significant abnormalities. Only AMS and FNS were found to be statistically significant in predicting abnormal scans. Patients with AMS had a 2.5 times (95% CI: 1.1 to 5.8) higher odds for an abnormal scan compared to those without AMS, adjusting for FNS. Patients with FNS had adjusted odds of 8.9 (95% CI: 4.2 to 18.8). Conclusion: This study reports a high (59.6%) rate of abnormal adult non-trauma cranial CT compared with previous studies. Altered mental status and the presence of focal neurological sign are significant predictors for an abnormal scan. They should serve as useful criteria when devising utilisation strategies for emergency non-trauma cranial CT in future studies.
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