The rapid increase in antibiotic resistant strains of bacteria has led to an urgent need to develop new methods of treating bacterial infections. Antibacterial polymeric nanoparticles are of interest for...

1D core-shell nanoparticles are considered to be among the most promising for biomedical applications such as drug delivery. The versatile living crystallization-driven self-assembly (CDSA) seeded growth method allows access to...

In situ generation of the five-coordinate complex Ru(η 5 -Cp*)(PR 2 )(PPh 3 ) (2), via dehydrohalogenation of Ru(η 5 -Cp*)Cl(PR 2 H)-(PPh 3 ), has allowed its reactivity toward a range of small molecules to be compared with that of its well-studied analogue Ru(η 5 -indenyl)(PR 2 )(PPh 3 ) (1), in a study designed to assess the likelihood of variable hapticity in the chemistry of complex 1. Reactions of 2 with hydrogen, carbon monoxide, phenylacetylene, ethylene, acrylonitrile, and 1-hexene demonstrate enhanced nucleophilicity/basicity of the terminal phosphido ligand in 2 relative to that in complex 1. Complex 2 also exhibits greater lability of the PPh 3 ligand, leading to substitutional product mixtures that were not observed for 1. Both of these features are consistent with the more electron-rich and sterically imposing nature of the Cp* ligand in 2 relative to the indenyl ligand in 1. Nevertheless, the fundamental transformations of the phosphido ligand are comparable for the two complexes. This suggests that variable hapticity does not play a role in reactions of indenyl complex 1, since η 5 −η 3 shifts are unlikely to occur for Cp* complex 2. The implications of these reactivity studies for the design of highly active, yet stable, ruthenium half-sandwich catalysts for hydrophosphination are discussed.

As nucleic acid (NA) technologies continue to revolutionize medicine, new delivery vehicles are needed to effectively transport NA cargoes into cells. Uniform and length-tunable nanofiber micelleplexes have recently shown promise...

Earl, John Campbell and Parkin, H M. 1935. "The fastness of certain amino-azo dyes to washing." Journal and proceedings of the Royal Society of New South Wales 68(2), 110-111.