Both the CPM and CPT therapies seemed to be beneficial for the treatment of AC in DM patients, however CPM revealed more distinctive improvements in the function and pain levels of the AC patients.
AMAÇ: 1990-2009 yılları arasında İnflamatuvar barsak hastalığı (İBH) tanısı alan hastaların sosyo-demografik, klinik özellikleri ile teşhis ve tedavilerinin retrospektif olarak incelenmesi amaçlandı.GEREÇ VE YÖNTEM: 1990-2009 yılları arasında Tıp Fakültesi Gastroenteroloji Kliniğinde İBH tanısı alan 237 hastanın dosya kayıtları incelenerek yapılmıştır. Hastaların yaş, cinsiyet, sigara kullanımı, endoskopi ve histopatoloji bulguları, hastalarda gelişen lokal ve sistemik komplikasyonlar, uygulanan tedavi tipleri ve cerrahi tedavi nedenleri incelenmiş ve karşılaştırılmıştır. BULGULAR: 1990 ile 2009 yılları arasında 144 Ülseratif Kolit, 73 Crohn Hastalığı ve 20 İndetermine Kolit hastası takip edildi. Ülseratif Kolit'li hastaların teşhis anındaki tanı yaşı ortalaması 37 yıl idi. Hastaların %28,7'sinde sol kolon tutulumu, %25,2'inde pankolit ve %21 proktit tablosu mevcuttu (p<0.01). Sistemik komplikasyon olarak bir hastada eritema nodosum, üç hastada sakroileit, üç hastada primer sklerozan kolanjit, bir hastada da malign dönüşüm görüldü. Crohn hastalığı tespit edilen hastaların yaş ortalaması 35 yıl idi. Hastaların %34'ünde kolon, %64,2'sinde ince barsak tutulumu saptandı. Sistemik komplikasyon olarak dört hastada üveit, beş hastada sakroileit görüldü. 222 hasta 5-aminosalisilat (5-ASA) bilesiği tedavisi alıyordu. Immünsupresif tedavi alan 6 hasta saptandı. 159 hasta monotedavi (5-ASA), 19 hasta kombine tedavi alıyordu.
SONUÇ:Hastalığın klinik seyrinin ve klinik tablosunun belirlenmesi, uygulanacak tıbbi ve cerrahi tedavileri ve farklı subgrup hastaların takip stratejilerini saptamak için önemlidir.
Superior mezenter arter (SMA) sendromu duodenumun üçüncü kıtasının aorta ve SMA proksimal kısmı arasında basıya uğraması sonucu ortaya çıkan ve nadir görülen bir klinik tablodur. Belirgin kilo kaybı ile birlikte giden bulantı, kusma, anoreksiya, epigastrik ağrı ve şişkinlik başlıca yakınmalardır. Sık karşılaşılan nedenlerle açıklanamayan hızlı kilo kaybı, atipik ve tekrarlayan obstrüktif bulguları olan hastalarda SMA sendromu düşünülmelidir. Bu yazıda atipik şikayetleri olması nedeniyle tanı güçlüğü yaşayan hastanın yaşam kalitesini uzun süre bozan superior mezenter arter sendromlu bir olgu sunulmuş tanı ve tedavi yöntemleri tartışılmıştır.
Objectives: This study aims to determine femoral cartilage thickness using ultrasonography in familial Mediterranean fever (FMF).
Patients and methods: A total of 45 patients (16 males, 29 females; mean age: 38.5±9.1 years; range, 24 to 49 years) with the diagnosis of FMF and 31 healthy individuals (6 males, 25 females; mean age: 37.0±8.7 years; range, 25 to 47 years) between January 2016 and July 2016 were included in this study. Clinical data and demographic characteristics of the patients were recorded. All FMF cases in the study were in remission with colchicine treatment. The thickness of femoral cartilage in both knees were evaluated using ultrasonography. Three measurements (mid-point) were taken from both knees (at the medial/lateral femoral condyles and intercondylar area).
Results: Ultrasonographical measurements revealed that cartilage measurements of FMF patients were significantly thinner at both the medial/lateral femoral condyles and intercondylar area on the right knee and at the medial/lateral femoral condyles on the left knee (p<0.001). The cartilage measurements in FMF patients were significantly thinner at the intercondylar area on left knee, compared to those in controls (p=0.023).
Conclusion: Our study showed decreased femoral cartilage thickness in FMF patients. These findings indicate that even if these patients do not have an attack, they may have subacute and chronic arthritis in their joints, and their femoral cartilage thickness can be affected.
<b>Objective:</b> There is still no diagnosis method with high sensitivity and specificity for COVID-19. Patient complaints, real-time reverse transcription-polymerase chain reaction (RT-PCR), inflammatory markers, clinical prognosis, and the degree of involvement in the chest CT, if necessary are evaluated in an effort to make a diagnosis. Delays in diagnosis have led to a rapid spread of the disease. This study aims to evaluate the effectiveness of the inflammatory markers and to determine the follow-up process of the patients by assessing the impact of the treatments administered on RT-PCR test results.<br />
<b>Material and methods: </b>Files of 150 patients monitored in the wards with suspected COVID-19 are analyzed retrospectively. Patients were selected among those who underwent laboratory tests, RT-PCR testing and Thoracic CT within the first 24 hours of admission. Patients were divided into 5 groups based on the severity of involvement in Thoracic CT. Inflammatory markers were compared among the groups. Impact of the administered treatments on follow-up RT-PCR test results was evaluated.<br />
<b>Results: </b>Studied inflammatory markers were in normal ranges and similar across all CORADS groups. Only the C-Reactive Protein (CRP) and Ferritin levels were showing an increase in accordance with CORADS severity. Mean time to testing negative on RT-PCR was 10 days across all treatment groups. Times to testing negative among patients receiving other treatments were similar.<br />
<b>Conclusion: </b>Among the inflammatory markers, CRP and Ferritin values are correlated with CORADS severity. Administered COVID-19 treatments have similar impact on RT-PCR test results.
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