Thirty samples were collected from patients (١٠-٤٥) years old, suffered from tonsillitis,pharyngitis, infected wounds, acne & Bronchitis. Gram -positive bacteria were isolated from these samples, and diagnosed, of which, Staphylococcus aureus ( ٥٠%) and Staphylococcus epidermidis (١٦.٦٦%), Streptococcus pyogenes (١٣.٣٤%), Streptococcus pneumoniae (١٠%) and Micrococcus spp (١٠%). Alcoholic and water extracts of the punica granatum(Pomegranate) peels as well as the dried powders were prepared, the effect of these extracts were studied against these isolates. The antimicrobial susceptibility tests of the extracts were determined by Kirby-Bauer method and the MICs were determined. The antibacterial activity of punica granatum(Pomegranate) peels was determined. The alcoholic extract showed more potent inhibitory effect on the isolates than water extract, and the best effect was on the growth of Staphylococcus epidermidis followed by Staphylococcus aureus , Micrococcus spp, Streptococcus pyogenes and Streptococcus pneumoniae. The zone of inhibition was (١٧-٢٣mm) for alcoholic extract and( ١٢-٢٣mm) for watery extract. The antibacterial activity of pomegranate peels extracts should make it useful for treatment of wounds, skin infections, tonsillitis and pharyngitis caused by the above bacteria.
Thirty five samples were collected from patients (1-30) years old, suffered from, infected skin , rushes, boils , oral thrush, anal & vaginal itches. Candida albicans 57.3% (20 isolates) and Candida tropicalis 22.5% (8 isolates) Aspergillus fumegatus 11.5% (4 isolates) Aspergillus nigar 8.7%(3 isolates) , were isolated & identified from these samples. Alcoholic & water hot extracts of the punica granatum (Pomegranate) peels as well as the dried powder were prepared. The anti-fungal activity of the extracts was evaluated by means of the agar-well diffusion assay. The extract exhibited potent activity against yeast. The Minimum inhibitory concentrations were 128-1024 μg/ml against Candida albicans and Candida tropicalis .Their was little difference between the activities of alcoholic extract & aqueous extract. These results suggest the Pomegranate Peels extract which contains gallotanic acid as a promising anti-fungal agent. Key wards : Antifungal agents, Plant extracts, Candida isolation
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