The present study aimed to investigate clinico-pathological changes on turkey poult infected with Pasteurella Multocida (P. Multocida), about 200 turkey poults, 15 th day old, were subjected for bacteriological examination to obtain 80 healthy turkey poults free from any bacterial infection. Turkey poult were divided to 4 equal group, 1 st Gp healthy poults non treated (control), 2 nd Gp healthy poults injected with 20 mg/kg bwt. spectinomycin for 5 days, 3 rd Gp infected non treated turkey poults and 4 th Gp infected poults treated with 20 mg/kg b. wt spectinomycin for 5 days. Clinical signs, mortality rate and post mortom examination were recorded. Effect of P. Multocida and spictinomycin on body weight was studied. At the end of treatment (1 st day post treatment) 5 poults from each group were sacrificed, blood samples were taken for hemato-biochemical analysis. Samples from liver and kidney for detection of spectinomycin residue, beside samples from internal organs were taken for pathological study.Turkey poults received spectinomycin showed significant increase in weight gain, improve feed conversion rate, significant decrease in RBCs, Hb, PCV% and insignificant effect in leukogram, total protein, albumin, globulin, AST , ALT, ALP, uric acid, creatinine, serum total lipid, cholesterol and triglyceride as compared with healthy non treated group Pasteurellosis in turkey showed clinical signs of loss of appetite, depression, ruffled feathers, dropping of the wings, fever, diarrhea, poor growth, emaciation as well as cyanosis of comb and wattles and mortality rate was 25 %. Significant reduction in body weight, weight gain, RBCs, PCV%, Hb and significant elevation in feed conversion rate, WBCs, monocyte, globulin AST, ALT, ALP uric acid, creatinine and insignificant effect in heterophils, lymphocyts, Eosinophils, basophile, total lipid, cholesterol, triglyceride, total protein, albumin and A/G ratio .Spectinomycin residues were detected in liver and kidney up to 9 days post treatment but not detected at 12 days post treatment and its residues in kidney higher than in liver.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.