Myocardial infarction is one potential outcome after an electric shock although it is seen relatively rarely and its pathogenesis remains controversial. Coronary arteriography is the most helpful investigation in assessing the physiopathology of the rare event. These patients merit a careful scrutiny due to an increased death rate because of cardiopulmonary arrest. Here, we reported a man with inferior myocardial infarction following electrical shock. Although he had frankly normal coronary arteries by coronary angiography, myocardial infarction was objectively evident by cardiac enzymes, electrocardiography and echocardiography. Amputation was performed on his left wrist from the elbow and fasciotomy was performed on his right wrist due to compartment syndrome. Electrocardiography changes returned to normal level within 6th hours of electric shock. He was discharged in good health after stabilization.
ÖZETPatogenezi tartışmalı olmasına ve nadiren görülmesine rağmen, miyokart enfarktüsü bir elektrik çarpmasından sonra potansiyel bir sonuçtur. Bu nadir olayın patofizyolojinin değerlendirilmesinde koroner arteriografi en iyi yardımcı araştırma yöntemidir. Bu hastalar kardiyopulmoner arresten dolayı artan bölüm oranlarından dolayı ciddi bir bakımı hak ediyorlar. Burada elektrik çarpmasını takibe miyokart enfarktüsü gelişen bir vaka bildirdik. Koroner anjiyografisi tamamen normal olmakla beraber miyokart enfarktüsü kardiyak enzimler ve elektrokardiyografi ile objektif olarak kanıtlandı. Sol el bileği dirsekten itibaren ampute edildi ve sağ el bileğine kompartman sendromundan dolayı fasiyotomi uygulandı. Elektrik çarpmasının altıncı saatinde elektrokardiyografideki değişiklikler normale döndü. Hasta stabilize edildikten sonra şifa ile taburcu edildi.
Women with valvular heart disease have an increased risk of adverse outcomes in pregnancy; however, with appropriate evaluation and treatment, most women can successfully bear healthy children. During pregnancy, pulmonary stenosis is generally well tolerated in the absence of other haemodynamically significant lesions. We present a case of a multiparous woman,who is pregnant with her sixth child, with a severe pulmonary stenosis. She presented with exertional chest pain and dyspnea. She was managed successfully with balloon valvuloplasty.
Background/Aims: Common bile duct ligation (CBDL) in the guinea pig is a well-defined model of acalculous cholecystitis. Nitric oxide (NO) mediates smooth muscle relaxation by stimulating the activity of soluble guanylate cyclase. The aim of this study was to determine whether the NO/cyclic guanosine monophosphate pathway plays a role in gallbladder relaxant response after CBDL. Methods: Relaxant response of gallbladder muscle strips from CBDL and sham-operated guinea pigs was studied in vitro. Animals were treated with saline, aminoguanidine or an aminoguanidine + L-arginine combination in vivo. Concentration-response curves of papaverine, diethylamine/NO, YC-1, sildenafil and amrinone were obtained and relaxations in each group were calculated as the percent of the contractions induced by carbachol (10–6 M). Results: There was a significant decrease in the gallbladder muscle relaxant responses to these substances in CBDL and aminoguanidine groups compared with sham surgical controls. The decreased relaxant response was reversed by aminoguanidine + L-arginine but not by aminoguanidine alone. Conclusion: Decreased relaxant responses might be due to the reduced guanylate cyclase enzyme activity, but further studies are required.
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