Background: Pathogen reduction technology (PRT) effectively mitigates bacterial contamination in platelets but is more likely to produce low yield units.Although low dose transfusion using conventional platelets has not been associated with increased bleeding, these findings have not been reproduced with PRT-treated platelets.Study Design and Methods: Platelet transfusions in a tertiary adult hospital were retrospectively reviewed. Comparisons were made between PRT-treated regular (PRT-PR) and low (PRT-PL) yield platelets. Outcomes examined included the number of platelets and RBCs transfused, transfusion-free interval, and corrected count increment (CCI). Subgroup analyses were also performed on hematology-oncology inpatients and outpatients, as well as nonhematology-oncology patients.Results: Platelet utilization per patient remained mostly unchanged (mean 2.9-4.3 units per patient per month) even when the frequency of PRT-PL transfusion increased. Among 1402 patients examined, the number of platelets and RBCs transfused was not significantly different between patients first transfused with PRT-PR versus PRT-PL (mean number of platelet units = 2.8 vs. 3.1, p = 0.38; mean number of RBC units = 4.8 vs. 4.3, p = 0.93). Among 10,257 platelet transfusions examined, the transfusion-free interval (hazard ratio = 1.05, 95% confidence interval 1.00-1.10) and CCI (10.2 vs. 11.0, p = 0.70) were comparable between PRT-PR and PRT-PL units. Similar findings were observed in all subgroups, except for shortened transfusion-free intervals among hematology-oncology inpatients. Conclusion: PRT-PR and PRT-PL units may be used in an equivalent manner to maintain an adequate platelet inventory, since there was only a minor difference in time between transfusions.
The magnetostrictive properties of Hiperco, a magnetic alloy of iron, cobalt, and chromium, were investigated to determine its suitability as a material for electromechanical transducers. The relations between the magnetic and magnetostrictive characteristics of a material and its performance as a transducer element are reviewed and criteria for its evaluation established. The properties of Hiperco, measured after a suitable heat treatment had been determined, are discussed in relation to these criteria and a comparison made with nickel and Permendur. For operation at magnetic remanence Hiperco is shown to be as good as Permendur for hydrophone applications, but inferior to nickel and Permendur when used as an underwater projector at high power levels. When polarized above remanence maximum value of 0.17 for the electromechanical coupling coefficient is realized and operation as a projector is improved. Performance data are given for a small underwater transducer constructed of Hiperco operating at remanence.
An experimental investigation of the longitudina l circumferential vibration s of magnetostrictive rings is the subject of this report. Two methods of exciting several orders of these mode s of vibration by means of magnetostriction are described. Sensitivit y curve s and radiation patterns of exper imental transducers operating in these mode s are presented.
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