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Objective: To compare the mean reduction in pain scores between Bonding agent (GLUMA® Comfort® Bond+ Desensitizer, and Fluoride varnish. Methodology: The study was conducted at Operative Dentistry, Department at Altamash Institute of Dental Medicine, Karachi from July 2015 to August 2016. Total 152 patients were selected. Patients were randomly allocated into two groups A and B. Gluma comfort bond plus desensitizer® was applied to the patients in group A and Duraphet® was applied to the patients in group B. Initial assessment was done after the application of the above products and thermal test was performed. The outcomes were based on a Visual Analogue Scale (VAS). Re-Evaluation was done again after 30 days of treatment in terms of mean reduction in pain from baseline by applying thermal test on visual analogue scale. Results: The average age of the patients was 37.4 ±8.38 years. After 30 days, mean Visual Analog Scale was significantly low in Group A i.e. 2.95±0.0.86 as compared to Group B i.e. 4.01±0.79(p=0.0005). Significant more reduction in mean pain score was observed in Bonding agent (Gluma desensitizer) as compared to Fluoride varnish Duraphat. Conclusion: In our study we found that bonding agent ( Gluma Desensitizer) is more effective in treating Dentine Hypersensitivity compared to fluoride varnish (Duraphat desensitizer group).

1 for ensuring that their final-year students were given the opportunity to respond to the increasing need in the health care system during these challenging times. We also commend these students for their willingness to join the workforce amidst rising fears and concerns of the COVID-19 pandemic, which shows they are ready for their lifelong call as frontline staff. The same opportunity was offered to final-year U.K. medical students through the interim Foundation Year (iFY) programme 2 before they formally started Foundation Year 1 (FY1), comparable to an internship, in August 2020. However, the accelerated graduation and deployment of the new physician cohort into the workforce has had negative consequences.