RationaleA robust finding in the alcohol literature is that heavy and alcohol-dependent drinkers show stronger reactions to alcohol-related cues than light drinkers. However, there are individual differences in the degree of cue-elicited craving. Personality factors appear to be involved in cue reactivity and impulsivity is a possible candidate.ObjectivesThe aim of the present study was to examine the role of different aspects of impulsivity in heavy drinking and alcohol cue reactivity in social drinkers.MethodsParticipants were heavy (n = 13) and light (n = 29) social drinkers who were exposed to neutral and alcohol-related stimuli during a single laboratory session. Trait impulsivity, response inhibition, and sensitivity to reward were assessed with the Barratt Impulsiveness Scale (BIS-11), the Stop Signal Task, and the Card-Arranging Reward Responsivity Objective Test, respectively.ResultsHeavy drinkers scored higher on trait impulsivity (BIS-11) than light drinkers. In addition, heavy drinkers reported elevated levels of craving for alcohol, but both in light and heavy drinkers, craving increased equally after exposure to alcohol cues. Impulsivity appeared to moderate this relation: heavy drinkers with ineffective response inhibition showed more craving to alcohol cues, compared to heavy drinkers with adequate response inhibition. In light drinkers, response inhibition did not influence craving to alcohol cues.ConclusionsDifferent aspects of impulsivity are involved in heavy drinking and perhaps motivate alcohol consumption in a variety of ways. Having a deficient response inhibition appears to be a risk factor for heavy drinkers because it is associated with increased craving to alcohol cues.

The results clearly implicate both trait impulsiveness and response inhibition in the modulation of cue-elicited craving in alcohol dependence. Theoretical and methodological issues in the findings and their clinical implications in alcohol treatment and relapse are discussed.

Both cue-elicited craving and impulsivity have been involved in alcohol misuse. However, their role in relapse has not been very clear. In the present study, we ask whether cue-elicited craving, impulsivity, and their interaction term predict a lapse in problem drinkers. Participants (n=20) were former patients of the clinic, U-Center, in the Netherlands, who had completed a six-week alcohol treatment program and had an abstinence goal. While in treatment, they underwent a cue exposure paradigm in a real alcohol-related setting and their trait impulsivity was measured with the Barratt Impulsiveness Scale version 11 (BIS-11). During the follow-up assessment, patients were contacted again and asked about their alcohol drinking behavior during the first three months after the end of the treatment program. It was found that higher craving and lower trait impulsivity levels are associated with a higher probability of a lapse.