A facile
synthesis of benzo[3,4]indolo[1,2-b]isoquinolin-8-ones
is described. Under copper catalysis, the reaction proceeds with a
high efficiency and a broad reaction scope. A deuteration experiment shows that the KIE value is 2.85. From the results on mechanism
studies, copper-catalyzed C–H activation, intramolecular cis-addition of alkynes, and reductive elimination are involved.
Moreover, this skeleton is indeed a new fluorophore, and its photophysical
properties are also investigated.
A convenient and efficient method for one pot synthesis of polysubstituted (Z)-halobenzo [c,d]indoles from 8-alkynyl-1naphthylamine derivatives using CuCl 2 and CuBr 2 as the halogenated reagents has been developed. In this protocol, both (Z)-chloro and bromobenzo[c,d] indole derivatives can be obtained in moderate to good yields by copper halide-promoted stereoselective intramolecular cis-addition annulation reactions. A novel fluorescent molecule with AIE properties was constructed via Suzuki coupling reaction and its optical properties was investigated, which made them possible candidates for optoelectronic conjugated materials.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.