A 29-year old had been admitted to our institution with acute onset of schizophreniform psychosis after 5-day administration of sustained-release bupropion hydrochloride, which had been prescribed for nicotine withdrawal in a daily dosage of 300 mg. Examination results were found to be completely normal, apart from a positive drug screen for cannabis. We hypothesize that bupropion had induced psychotic symptoms in this patient.
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