A floatation centrifugation procedure is described by which antibodies and non-specific rubella virus haemagglutination inhibitors can be completely separated. Using this method it was shown that false positive reactions occur with the conventional pretreatments of sera for removing inhibitors, especially with the heparin-McCl2 procedure. Other methods for removal of inhibitors were examined in view of recent knowledge about the chemical nature of the inhibitors. Treatment with phospholipase C proved useful for disclosure of false positive reactions, while floatation centrifugation was the most sensitive method for demonstration of low antibody concentrations.
The prognosis of giant and spindle cell carcinoma of the thyroid is extremely poor. It does appear, however, that a multisciplinary approach to treatment of this aggressive cancer is more effective than a single-treatment modality. Operative ablation of gross tumor, postoperative irradiation therapy, and chemotherapy have demonstrated encouraging results. A different therapeutic approach with the addition of immunotherapy to surgical resection, postoperative irraditation, and chemotherapy is described in this case report. The preliminary result is encouraging.
SummaryThe resistance of RAE, Riisch, Mallinckrodt paediatric and Portex plain nasal and oral tracheal tubes with internal diameters 3.0 mm and 3.5 mm was calculated at air flows of 1 to 10 litres per minute. Theflow resistance profiles of RAE and Rusch tracheal tubes was generally higher than those of Mallinckrodt paediatric and Portex plain tubes. All RAE and Riisch nasotracheal tubes of size 3.0 mm internal diameter and orotracheal tubes 3.0 mm internal diameter had aflow resistance exceeding 3.0 kPa litreslsecond at an air flow of4 litreslminute. It is concluded that these tracheal tubes ought only to be used with assisted or controlled ventilation.
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