Sweet's syndrome (acute febrile neutrophilic dermatosis) is characterized by a constellation of clinical symptoms, physical features, and pathologic findings which include fever, neutrophilia, tender erythematous skin lesions (papules, nodules, and plaques), and a diffuse infiltrate consisting predominantly of mature neutrophils that is typically located in the upper dermis. Sweet's syndrome presents in three clinical settings: classical (or idiopathic), malignancy-associated, and drug-induced. Classical Sweet's syndrome (CSS) usually presents in women between the age of 30 to 50 years, is often preceded by an upper respiratory tract infection and may be associated with inflammatory bowel disease and pregnancy. We report here a case of classical sweets syndrome with the typical histopathological findings who reported well to treatment.
Polymyositis is rare as a stand-alone entity and is often misdiagnosed; most patients whose condition has been diagnosed as polymyositis have inclusion-body myositis, necrotizing autoimmune myositis, or inflammatory dystrophy. Polymyositis remains a diagnosis of exclusion and is best defined as a subacute proximal myopathy in adults who do not have rash, a family history of neuromuscular disease, exposure to myotoxic drugs (e.g. statins, penicillamine, and zidovudine), involvement of facial and extraocular muscles, endocrinopathy, or the clinical phenotype of inclusion body myositis. The etiology of polymyositis may be due to underlying systemic autoimmune diseases, viral, parasitic, bacterial infections or drug induced. Here we describe a case of juvenile polymyositis post viral infection with hepatitis A.
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