Figure I. Photographs show the left subglottic cyst pre-(A) and intraoperatively (B). Case report A lO-day-old boy, born full term via caesarean section and weighing 7 lb 11 OZ, was discharged home with no complic ations. At home , his mother noticed that the infant' s breathing had become progressively more congested. She sought medic al advice from a pedi atrici an. At the first visit, the boy' s abnormal breathing was attribut ed to a common cold. But despite conserva tive treatment, his
Only two cases ofjuvenile xanthogranuloma ofthe larynx have been pr eviously repo rted in the literature. We report a new case, which occurred in an 18-month-old girl. The patient was brought to us fo r treatment of stridor and respirat ory distress. During examination, she was fo und to have a subglottic mass. The lesion was treated with laser microlaryngoscopy, which relieved the patient's respiratory distress and obviated the need f or tracheotomy. Pathologic examination ofthe mass revealed that it was consistent with a j uvenile xanthogra nuloma. Juvenile xanthogranuloma is generally a benign and selflimiting disease, but complications can occur when the space that the tumor occupies causes fu nctional impairment.
Since the declaration of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in March 2020 by the World Health Organization (WHO), there has been an emergence of a new syndrome termed multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19. MIS-C is defined by the presence of fever, systemic inflammation and multiorgan dysfunction in association with SARS-CoV-2 infection or COVID-19 exposure. Knowledge of this syndrome’s presentation and pathophysiology is constantly evolving as more cases are reported in the literature. This case identifies a 3-month-old patient who tested negative for SARS-CoV-2 antigen, reverse transcriptase polymerase chain reaction (RT-PCR) and antibodies but qualified for MIS-C diagnosis. To the best of our knowledge and through extensive research at the time of diagnosing and reporting this condition to the healthcare authorities, we report the youngest pediatric patient with MIS-C diagnosis. We document this case to contribute to further understanding the variable manifestations of MIS-C and the importance of early diagnosis and treatment with intravenous immunoglobulin (IVIG).
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