The intelligence of science, technology, and innovation in today's world can be very influential. So, making a wrong decision can have irreparable consequences and may even hurt an economy or a country for several years. Considering that the upstream documents are the guidelines for determining the macro-policies of science and technology, it is necessary to analyze these documents to identify the components of National Powerness from the perspective of these documents. In this study, we sought to investigate the upstream documents and statements of the Supreme Leader to enumerate the dimensions and components of National Powerness. The method used was based on documentary study and to analyze the findings, the Content Analysis method was used. In the policy section, upstream documents such as the constitution, the vision of the I.R. Iran on the horizon of 1404, the declaration of the second step of the Islamic Revolution of Iran and other documents were examined. In the speeches section, statements of the Supreme Leader among scientific experts, university professors, industry, and technology activists, etc. were reviewed and analyzed. The themes extracted from these documents were classified into six dimensions: political, defense-security, environmental, economic, scientific, technological, and cultural discourse. Below these dimensions, 75 components were extracted. Depending on the extracted components, technology can be identified or ranked.
The novel coronavirus disease 2019 (COVID-19) still poses a serious threat to every human on the planet nearly 1.5 years after its beginning. Unfortunately, the current diagnostic methods, although highly sensitive and specific, still suffer from many shortcomings. Faster and easy-to-operate diagnostic systems are undoubtedly sorely needed. The CRISPR/Cas platform has gained much attention in recent years in a wide range of biomedical sciences. Besides its treatment potential and drug and vaccine development, it can be used for disease diagnosis. Thus, the CRISPR/Cas-based system holds great promise for providing a rapid and easily deployable COVID-19 detection and is on par with the conventional diagnostic approaches in terms of sensitivity and specificity. In this review article, we discuss the latest advances of CRISPR/Cas technology as a fast and reliable severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection method.
The newest member of the coronavirus family, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has caused a pandemic (after being endemic in Wuhan, China) and is threatening to the health of every person on the planet. Nearly 1.5 years after the coronavirus disease 2019 (COVID-19) worldwide challenges, a gold-standard, highly effective anti-viral therapy is still undiscovered. The urgency of this pandemic has forced all scientists to tackle this problem using any logical mode of therapy. One such approach is modulating and manipulating the host’s immune response using immunotherapy against SARS-CoV-2 infection and its collateral complications. This review article aims to present an update on the immunopathogenesis of SARS-CoV-2, and how it, directly and indirectly, deteriorates the patients’ condition. The latest findings of preclinical and clinical trials using passive immunotherapy in the context of the COVID-19 are compiled as well.
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