Retinal image analysis is a challenging problem due to the precise quantification required and the huge numbers of images produced in screening programs. This paper describes a series of innovative brain-inspired algorithms for automated retinal image analysis, recently developed for the B Bart M. ter Haar Romeny B.M.terHaarRomeny@tue.nl 123 B. M. ter Haar Romeny et al.optic nerve head detection, crossing-preserving enhancement and segmentation of retinal vasculature, arterio-venous ratio, fractal dimension, and vessel tortuosity and bifurcations. Many of these algorithms outperform state-of-the-art techniques. The methods are currently validated in collaborating hospitals, with a rich accompanying base of metadata, to phenotype and validate the quantitative algorithms for optimal classification power.
The combination of artificial intelligence technology and medical science has inspired the emergence of medical robots with novel functions that use new materials and have a neoteric appearance. However, the diversity of medical robots causes confusion regarding their classification. In this paper, we review the concepts pertinent to major classification methods and development status of medical robots. We survey the classification methods according to the appearance, function, and application of medical robots. The difficulties surrounding classification methods that arose are discussed, for example, (1) it is difficult to make a simple distinction among existing types of medical robots; (2) classification is important to provide sufficient applicability to the existing and upcoming medical robots; (3) future medical robots may destroy the stability of the classification framework. To solve these problems, we proposed an innovative multilevel classification strategy for medical robots. According to the main classification method, the medical robots were divided into four major categories鈥攕urgical, rehabilitation, medical assistant, and hospital service robots鈥攁nd personalized classifications for each major category were proposed in secondary classifications. The technologies currently available or in development for surgical robots and rehabilitation robots are discussed with great emphasis. The technical preferences of surgical robots in the different departments and the rehabilitation robots in the variant application scenes are perceived, by which the necessity of further classification of the surgical robots and the rehabilitation robots is shown and the secondary classification strategy for surgical robots and rehabilitation robots is provided. Our results show that the distinctive features of surgical robots and rehabilitation robots can be highlighted and that the communication between professionals in the same and other fields can be improved.
A well-established method for diagnosis of glaucoma is the examination of the optic nerve head based on fundus image as glaucomatous patients tend to have larger cup-to-disc ratios. The difficulty of optic segmentation is due to the fuzzy boundaries and peripapillary atrophy (PPA). In this paper a novel method for optic nerve head segmentation is proposed. It uses template matching to find the region of interest (ROI). The method of vessel erasing in the ROI is based on PDE inpainting which will make the boundary smoother. A novel optic disc segmentation approach using image texture is explored in this paper. A cluster method based on image texture is employed before the optic disc segmentation step to remove the edge noise such as cup boundary and vessels. We replace image force in the snake with image texture and the initial contour of the balloon snake is inside the optic disc to avoid the PPA. The experimental results show the superior performance of the proposed method when compared to some traditional segmentation approaches. An average segmentation dice coefficient of 94% has been obtained.
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