Background: Giant lip hemangioma is a rare disease that may cause difficulty in preoxygenation and ventilation when using facemasks and intubation during general anesthesia induction.Case: A laparoscopic cholecystectomy was planned for a 77-year-old woman. The patient had a giant lower lip hemangioma that was 12 x 5 x 5 cm, which made preoxygenation and ventilation through a face mask impossible and put her at risk of hemangioma rupture. We preoxygenated her through a high-flow nasal cannula. Following propofol and succinylcholine administration, we intubated the patient with a video laryngoscope without desaturation, hemangioma rupture, or CO 2 retention.Conclusions: High-flow nasal cannula is a useful tool when difficult intubation is expected in patients who have problems using conventional facemasks.
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