procedure has two disadvantages. One, the amount of derivative is about 10 times less than the amount detected by the procedure in reference 7 because of the limited amount of ethanol. Two, the resolution of the ethyl lactate heptafluorobutyrate peak from the trichloroethyl heptafluorobutyrate peak is extremely poor. A much better method for the EC-GLC determination of lactic acid is presented in a previous paper (7). The trichloroethyl ester of formic acid is also very poorly resolved from the trichloroethyl heptafluorobutyrate. Although the application of this procedure to other types of carboxylic acids presents problems, it has been demonstrated in this paper that it is a simple and sensitive EC-GLC method for detecting many of the short chain acids in spent culture media and in body fluids.
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