Dipeptide repeat
proteins (DRPs) are considered a significant cause
of amyotrophic lateral sclerosis (ALS), and their liquid–liquid
phase separation (LLPS) formation with other biological molecules
has been studied both in vitro and in vivo. The immobilization and
wetting of the LLPS droplets on glass surfaces are technically crucial
for the measurement with optical microscopy. In this work, we characterized
the surface diffusion of LLPS droplets of the DRPs with different
lengths to investigate the multivalent effect on the interactions
of their LLPS droplets with the glass surface. Using fluorescence
microscopy and the single-particle tracking method, we observed that
the large multivalency drastically changed the surface behavior of
the droplets. The coalescence and wetting of the droplets were accelerated
by increasing the multivalency of peptides in the LLPS system. Our
findings on the effect of multivalency on interactions between droplets
and glass surfaces could provide a new insight to enhance the understanding
of LLPS formation and biophysical properties related to the solid/liquid
interface.
Cellulose‐based conductive gels are representative nanomaterials and have a good flexibility, biodegradability, and biocompatibility due to the cellulose. Therefore, they are considered as important candidates for the development of next generation nanoarchitectonics materials for electronics and green energy. To date, conductive cellulose gels have been widely investigated for various applications, including sensors, energy storage devices, energy generators, and actuators. A number of studies has shown that cellulose‐based conductive gels have a superior performance compared to gels prepared using petroleum‐derived chemicals. Therefore, in this review, we will introduce the general preparation method of cellulose‐based conductive gels in order to present the latest research results and to provide information for future nanoscience and research studies. Also, the main applications of cellulose‐based conductive gels and the progress of their research will be described.
Carbonized C60 nanospheres efficiently improve the mechanical properties and supercapacitor performance when they are added to a poly(vinyl alcohol)/TEMPO-cellulose hydrogel-based electrolyte.
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