An operationally simple, green and efficient procedure for one-pot synthesis of novel polycyclic heteroaromatic compounds such as benzamidonaphtho[2,1-b]furans and benzamidobenzo[b]furans has been developed from the reaction of arylglyoxals, benzamide, and phenols. The reactions were mediated with low amounts of yttrium nitrate hexahydrate as a suitable Lewis acid catalyst without using solvent.
Zirconium Catalyzed Chemoselective Synthesis of New Amido-Substituted Benzo[b]furans via a One-Pot Reaction. -The one-pot three-component reaction of arylglyoxals (II), benzamide (III) and phenol derivatives (I) and (V) in the presence of a Zr-catalyst affords chemoselectively benzofurans (IV) and (VI), resp., rather than alternative oxazole derivatives. -(KARAMI, B.; KHODABAKHSHI, S.; VAHABINIA, H. R.; Heterocycles 87 (2013) 2, 399-405, http://dx.doi.org/10.3987/COM-12-12621 ; Dep. Chem., Yasouj Univ., Yasouj 75918, Iran; Eng.) -S. Karsten 22-108
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