Knowledge and competency of human resources are valuable assets of an organization and human resource actions are the major tools through which organizations can exploit skills, attitudes, and behaviors of people to do their tasks and fulfill organizational purposes. The present study explores the relationship between effectiveness of human resource management actions and organizational agility. It is applicable from objective aspect and descriptive-field-correlational from methodological aspect. The statistical population included all experts and managers of the selected branches of Melli Bank in Isfahan Province. Stratified random sampling method was employed for sampling and the sample size was estimated equal to 310. The results disclosed that there is a positive and significant relationship between effectiveness of human resource management actions in various fields of training, selection and recruitment, compensation and performance evaluation with organizational agility.