Non-enzymatic hydrogen peroxide sensor was constructed and designed by electrodeposition of silver nanoparticles on a modified glassy carbon electrode (GCE) with an electrochemically reduced graphene oxide (ERGO) and cobalt oxide (Co 3 O 4 ) film. The characterization of Ag NPs/Co 3 O 4 /ERGO/GCE was carried out by scanning electron microscopy, cyclic voltammetry, and chronoamperometry. The result of scanning electron microscopy demonstrated Ag NPs were dispersed on the Co 3 O 4 /ERGO composite. Electrochemical measurements revealed that the Ag NPs electrodeposition on the Co 3 O 4 film provides an electrode with boosted current of reaction, sensitivity, and outstanding stability. The sensor displayed superior linearity in the concentration range of 50 μM to 1.1 mM with a detection limit of 0.84 μM (S/N=3) and showed high sensitivity (2950 μA mM −1 Cm −2 ).
Designing a novel platform capable of providing a proper tissue regeneration environment is a key factor in tissue engineering. Herein, a green composite based on gelatin/agarose/zeolite with pomegranate peel extract was fabricated as an innovative platform for tissue engineering. Gelatin/agarose was loaded with pomegranate peel extract-loaded zeolite to evaluate its swelling behavior, porosity, release rate, and cell viability performance. The composite characteristics were evaluated using XRD and DSC. The hydrogel performance can be adjusted for the desired aim by zeolite content manipulation, such as controlled release. It was shown that the green nanocomposite exhibited proper cellular activity along with a controlled release rate. Moreover, the hydrogel composite’s swelling ratio was decreased by adding zeolite. This study suggested a fully natural composite as a potential biomaterial for tissue engineering, which opens new ways to design versatile hydrogels for the regeneration of damaged tissues. The hydrogel performance can be adjusted specifically by zeolite content manipulation for controlled release.
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