Background/ Purpose: The assessment of QoL grew, yet little attention had been given to QoL of university students. We aimed to study quality of life in different Egyptian university students, find the prevalence of irritable bowel syndrome among university students and the relation of IBS to QoL. Methods: 656 students were included in the study 82 from each faculty, two questionnaires (quality of life and ROME IV) were handed over to students of Faculties of Medicine and Education in Mansoura, Alexandria, Port Said and Assiut Universities. Results: Only 365 students completed the questionnaire, Medical students had significantly lower QoL than students in Faculty of Education (median score of QoL in medical students = 127 vs 152 in non-medical students). Male students (median score of QoL = 142) had higher QoL than female students (median score of QoL = 134). Younger students had higher QoL scores in all dimensions than older students (median score of QoL = 147 vs 129). Only 40 students had IBS (11%). Conclusion: Medical students had significantly lower QoL than non-medical students. Male and younger students had significantly higher QoL than female and older students respectively. Prevalence of IBS among students was 11%.
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