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Segmentation of skin lesions plays a very important role in the early detection of skin cancer. However, indistinguishability due to various artifacts such as hair and contrast between normal skin and lesioned skin is an important challenge for specialist dermatologists. Computer-aided diagnostic systems using deep convolutional neural networks are gaining importance in order to cope with difficulties. This study focuses on deep learning-based fusion networks and fusion loss functions. For the automatic segmentation of skin lesions, U-Net (U-Net + ResNet 2D) with 2D residual blocks and 2D volumetric convolutional neural networks were fused for the first time in this study. Also, a new fusion loss function is proposed by combining Dice Loss (DL) and Focal Tversky Loss (FTL) to make the proposed fused model more robust. Of the 2594 image dataset, 20% is reserved for test data and 80% for training data. In test data training, a Jaccard score of 0.837 and a dice score of 0.918 were obtained. The proposed model was also scored on the ISIC 2018 Task 1 test images, whose ground truths were not shared. The proposed model performed well and achieved a Jaccard index of 0.800 and a dice score of 0.880 in the ISIC 2018 Task 1 test set. In addition, it has been observed that the new fused loss function obtained by fusing Focal Tversky Loss and Dice Loss functions in the proposed model increases the robustness of the model in the tests. The proposed new loss function fusion model has outstripped the cutting-edge approaches in the literature.

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Segmentation of skin lesions from dermoscopic images plays an essential role in the early detection of skin cancer. However, skin lesion segmentation is still challenging due to artifacts such as indistinguishability between skin lesion and normal skin, hair on the skin, and reflections in the obtained dermoscopy images. In this study, an edge attention network (ET-Net) combining edge guidance module (EGM) and weighted aggregation module is added to the 2D volumetric convolutional neural network (Vnet 2D) to maximize the performance of skin lesion segmentation. In addition, the proposed fusion model presents a new fusion loss function by combining balanced binary cross-entropy (BBCE) and focal Tversky loss (FTL). The proposed model has been tested on the ISIC 2018 Task 1 Lesion Boundary Segmentation Challenge dataset. The proposed model outperformed the state-of-the-art studies as a result of the tests.